Essay on the essential facts extracted from publications concerning the debate on the efficacy of anti-depressants
Thomas, Céline
Promotor(s) : Tirelli, Ezio
Date of defense : 6-Sep-2013 • Permalink : http://hdl.handle.net/2268.2/626
Details
Title : | Essay on the essential facts extracted from publications concerning the debate on the efficacy of anti-depressants |
Author : | Thomas, Céline |
Date of defense : | 6-Sep-2013 |
Advisor(s) : | Tirelli, Ezio |
Committee's member(s) : | Hansenne, Michel
Quertemont, Etienne |
Language : | English |
Number of pages : | 75 |
Rameau keyword(s) : | Antidépresseurs Médicaments -- Efficacité Publications |
Discipline(s) : | Human health sciences > Pharmacy, pharmacology & toxicology Social & behavioral sciences, psychology > Animal psychology, ethology & psychobiology |
Commentary : | 0 annexe |
Institution(s) : | Université de Liège, Liège, Belgique |
Degree: | Master en sciences psychologiques, à finalité spécialisée en psychologie clinique |
Faculty: | Master thesis of the Faculté de Psychologie, Logopédie et Sciences de l’Education |
Abstract
[fr] In 2009 Irving Kirsch sent shockwaves through the scientific, pharmaceutical and wider health care community by publishing his work on the effectiveness of antidepressants. His study claimed that antidepressants comprise little more than active placebos, and suggested that the conscious concealing of that fact was the “dirty little secret” of the pharmaceutical companies. Since, the antidepressant efficacy is the object of heated debates. These debates take place on many different levels: clinical trials which compare antidepressant efficacy to placebo (with their focus relative efficacy, or on methodological issues), research and theories either trying to explain antidepressant efficacy (trough biological and cognitive mechanisms) or its inefficacy, focus on risks and adverse effects, focus on long term effects, etc. This paper aims to provide an overview of the current state of the antidepressant efficacy debate.
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